Diagnosing hypoxia in murine models of rheumatoid arthritis from reflectance multispectral images

Sophie Glinton; Amy J. Naylor; Ela Claridge

doi:10.1117/12.2286087

28 July 2017 Diagnosing hypoxia in murine models of rheumatoid arthritis from reflectance multispectral images

Sophie Glinton, Amy J. Naylor, Ela Claridge

Proceedings Volume 10411, Clinical and Preclinical Optical Diagnostics; 1041109 (2017) https://doi.org/10.1117/12.2286087
Event: European Conferences on Biomedical Optics, 2017, Munich, Germany

Abstract

Spectra computed from multispectral images of murine models of Rheumatoid Arthritis show a characteristic decrease in reflectance within the 600-800nm region which is indicative of the reduction in blood oxygenation and is consistent with hypoxia.

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Sophie Glinton, Amy J. Naylor, and Ela Claridge "Diagnosing hypoxia in murine models of rheumatoid arthritis from reflectance multispectral images", Proc. SPIE 10411, Clinical and Preclinical Optical Diagnostics, 1041109 (28 July 2017); https://doi.org/10.1117/12.2286087

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KEYWORDS

Multispectral imaging

Hypoxia

Principal component analysis

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