Investigation of biosensor devices based on bacteriorhodopsin as a biological transducer

Amarjeet S. Bassi

doi:10.1117/12.2283891

29 August 2017 Investigation of biosensor devices based on bacteriorhodopsin as a biological transducer

Amarjeet S. Bassi

Proceedings Volume 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging; 103132N (2017) https://doi.org/10.1117/12.2283891
Event: Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 2002, Ottawa, Ontario, Canada

Abstract

The long-term objectives of this research are to focus on the development of nanobiosensor devices based on bacteriorhodopsin (bR)suitable for applications in the areas of environmental monitoring and testing. Such biosensors may be interfaced directly to mobile, autonomous or semi autonomous robotic devices or be applied as part of integrated "bio-chips" for field analysis applications. The specific and immediate goals of this research are to investigate the application of bR as an optical transducer and also investigate specific applications such as biosensors for toxicity monitoring based on bio-luminescent systems coupled to bateriorhodopsin which is used as the biological signal transducer. A biosensor is defined as a compact analytical device incorporating a biological or biologically-derived sensing element either integrated within or intimately associated with a physico-chemical transducer. The usual aim of a biosensor is to produce either discrete or continuous electronic signals which are proportional to a single analyte or a related group of analytes [1]. The biological sensing element can be an enzyme, antibody,nucleic acid, antibody fragment, or a whole microbial cell, or plant or animal tissue.

Citation Download Citation

Amarjeet S. Bassi "Investigation of biosensor devices based on bacteriorhodopsin as a biological transducer", Proc. SPIE 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 103132N (29 August 2017); https://doi.org/10.1117/12.2283891

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