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An investigation was made to evaluate currently used subtraction radiography techniques. The first order subtraction technique was found to be adequate for conventional clinical use. However when using fine grain high contrast films for the originals, the second order technique gave a more accurate subtraction image. The limiting factor in the sensitivity of the radiographic subtraction technique for detecting small contrast changes over an area of about 2 cm in diameter was found to be film noise and not quantum statistics. Extra fine grain films were compared with conventionally used films. While these extra fine grain films gave slightly better results, they also required x-ray exposures which would be too high for routine clinical use.
Michael G. Ort andEarle C. Gregg
"Characteristics And Limitations Of Photographic Films Used In Subtraction Radiography", Proc. SPIE 0070, Application of Optical Instrumentation in Medicine IV, (25 March 1976); https://doi.org/10.1117/12.954576
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Michael G. Ort, Earle C. Gregg, "Characteristics And Limitations Of Photographic Films Used In Subtraction Radiography," Proc. SPIE 0070, Application of Optical Instrumentation in Medicine IV, (25 March 1976); https://doi.org/10.1117/12.954576