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Photoacoustic imaging (PAI) detects ultrasonic signals from tissue optical absorption. Lipids, with strong absorption at 1.7 μm, are valuable for arteriosclerosis and myocardial infarction imaging. We introduce a high-speed wideband wavelength tunable Raman fiber laser for photoacoustic spectroscopy of lipids. Pump lasers adjust from 1560 to 1600 nm, with a 1 ns pulse width and 100 kHz repetition rate. The pump light combines with seed light and passes the Raman fiber. The seed light amplifies by matching the Raman gain spectrum generated through stimulated Raman scattering. We obtained photoacoustic images in the 1670 - 1720 nm range, demonstrating our lasers for lipid imaging.
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Sang Min Park, Seongjin Bak, Gyeong Hun Kim, Soon-Woo Cho, Hwidon Lee, Chang-Seok Kim, "High-speed wideband wavelength tunable Raman fiber laser for photoacoustic spectroscopy of lipids," Proc. SPIE PC12853, High-Speed Biomedical Imaging and Spectroscopy IX, PC128530P (13 March 2024); https://doi.org/10.1117/12.3003593