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13 March 2024 Suppression of the tailing effect for pathogen inactivation with UVC ultrashort pulsed light
Shundai Yamamoto, Kazuhiko Misawa, Hideki Abe
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Proceedings Volume PC12822, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2024; PC128220P (2024) https://doi.org/10.1117/12.3005990
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
In the inactivation of pathogens by ultraviolet light, the inactivation rate has been reported to decrease with increasing irradiation dose, commonly known as the tailing effect. In this study, we compared the inactivation effects between CW-LED and femtosecond pulsed laser for developing a new method to suppress such tailing effect. We found that femtosecond pulsed lasers suppressed the tailing effect and inactivated pathogens by more than one order of magnitude in comparison with CW-LED. The results of this study provide a new method for the practical application of bacterial inactivation by ultraviolet light.
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Shundai Yamamoto, Kazuhiko Misawa, and Hideki Abe "Suppression of the tailing effect for pathogen inactivation with UVC ultrashort pulsed light", Proc. SPIE PC12822, Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2024, PC128220P (13 March 2024); https://doi.org/10.1117/12.3005990
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KEYWORDS
Pathogens
Ultraviolet radiation
Femtosecond phenomena
Laser irradiation
Light absorption
Light emitting diodes
Nucleic acids
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