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While photoacoustic imaging can reach depths of several centimeters in soft tissue, bone tissue is hard to penetrate. Which is why so far, transcranial photoacoustic imaging has proved challenging to implement - with the main challenge being acoustic losses in the skull. Our overall goal is to investigate the feasibility of transcranial photoacoustic sensing and imaging, and to study its usefulness for monitoring hemodynamics. In this study we focus on the acoustic constraints imposed by the skull and present the initial results from our ex vivo human skull phantoms.
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Thomas Kirchner, Jan Laufer, "Photoacoustic signal propagation through human cranial bones," Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791K (9 March 2023); https://doi.org/10.1117/12.2650513