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13 June 2022 Design of DNA based dynamic devices, assemblies, and composites
Carlos Castro
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Proceedings Volume PC12054, Novel Patterning Technologies 2022; PC120540L (2022) https://doi.org/10.1117/12.2621401
Event: SPIE Advanced Lithography + Patterning, 2022, San Jose, California, United States
Abstract
DNA nanotechnology is a powerful approach for design of nanostructures with applications including single molecule sensing, drug delivery, and manipulating molecular components. We recently developed an approach that merges top-down and bottom-up design to enable DNA assemblies with complex geometries with many components, programmed dynamic properties, and the ability to actuate and assemble into higher order systems. We demonstrate this approach through fabrication of complex assemblies including a nanoscale DNA airplane. These assemblies are ideally suited to manipulate other nanoscale objects or materials. We recently demonstrated the ability to template reconfigurable assemblies of nanoparticles and apply tunable forces to biomolecules.
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Carlos Castro "Design of DNA based dynamic devices, assemblies, and composites", Proc. SPIE PC12054, Novel Patterning Technologies 2022, PC120540L (13 June 2022); https://doi.org/10.1117/12.2621401
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KEYWORDS
Nanolithography
Assembly equipment
Composites
Nanostructures
Molecular nanotechnology
Molecular self-assembly
DNA nanotechnology
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