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7 March 2022 Multimodal hybrid diffuse optics and ultrasound for screening for thyroid cancer
Pablo R. Fernández Esteberena, Gloria B. Aranda, Mauro Buttafava, Davide Contini, Lorenzo Cortese, Alberto Dalla Mora, Hamid Dehghani, Sixte de Fraguier, Felicia A. Hanzu, Giuseppe Lo Presti, Mireia Mora, An Nguyen Dinh, Antonio Pifferi, Marco Renna, Bogdan Rosinsky, Sabina Ruiz Janer, Mattia Squarcia, Paola Taroni, Alberto Tosi, Udo Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Lisa Kobayashi Frisk, Turgut Durduran
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Proceedings Volume PC11952, Multimodal Biomedical Imaging XVII; PC119520A (2022) https://doi.org/10.1117/12.2608941
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
Standard techniques for detection of thyroid cancer (ultrasound screening and fine-needle aspiration biopsy) have limited sensitivity and specificity, leading to a very large number of unnecessary thyroid extraction surgeries. With the aim of improving diagnosis, hybrid diffuse optics and ultrasound were used on nodules patients to obtain tissue hemodynamic information. Nodules rated 4A or 4B in the thyroid imaging reporting and data system (TI-RADS) are of clinical relevance and were classified using a logistic regression model built on our results. Fourteen benign and four malignant nodules were classified with a sensitivity of 100% and specificity of 77%.
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Pablo R. Fernández Esteberena, Gloria B. Aranda, Mauro Buttafava, Davide Contini, Lorenzo Cortese, Alberto Dalla Mora, Hamid Dehghani, Sixte de Fraguier, Felicia A. Hanzu, Giuseppe Lo Presti, Mireia Mora, An Nguyen Dinh, Antonio Pifferi, Marco Renna, Bogdan Rosinsky, Sabina Ruiz Janer, Mattia Squarcia, Paola Taroni, Alberto Tosi, Udo Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Lisa Kobayashi Frisk, and Turgut Durduran "Multimodal hybrid diffuse optics and ultrasound for screening for thyroid cancer", Proc. SPIE PC11952, Multimodal Biomedical Imaging XVII, PC119520A (7 March 2022); https://doi.org/10.1117/12.2608941
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KEYWORDS
Cancer
Ultrasonography
Diffuse optical imaging
Diagnostics
Imaging systems
Oxygen
Time resolved spectroscopy
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