Development of magnification tomosynthesis for superior resolution in diagnostic mammography

Raymond J. Acciavatti; Trevor L. Vent; Chloe J. Choi; E. Paul Wileyto; Peter B. Noël; Andrew D. A. Maidment

doi:10.1117/12.2580280

15 February 2021 Development of magnification tomosynthesis for superior resolution in diagnostic mammography

Raymond J. Acciavatti, Trevor L. Vent, Chloe J. Choi, E. Paul Wileyto, Peter B. Noël, Andrew D. A. Maidment

Proceedings Volume 11595, Medical Imaging 2021: Physics of Medical Imaging; 115951J (2021) https://doi.org/10.1117/12.2580280
Event: SPIE Medical Imaging, 2021, Online Only

Abstract

Our previous work showed that digital breast tomosynthesis (DBT) supports super-resolution (SR). Clinical systems are not yet designed to optimize SR; this can be demonstrated with a high-frequency line-resolution pattern. SR is achieved if frequencies are oriented laterally, but not if frequencies are oriented in the perpendicular direction; i.e., the posteroanterior (PA) direction. We are developing a next-generation tomosynthesis (NGT) prototype with new trajectories for the x-ray source. This system is being designed to optimize SR not just for screening, but also for diagnostic mammography; specifically, for magnification DBT (M-DBT). SR is not achieved clinically in magnification mammography, since the acquisition is 2D. The aim of this study is to investigate SR in M-DBT, and analyze how anisotropies differ from screening DBT (S-DBT). We have a theoretical model of a high-frequency sinusoidal test object. First, a conventional scanning motion (directed laterally) was simulated. In the PA direction, SR was not achieved in either S-DBT or M-DBT. Next, the scanning motion was angled relative to the lateral direction. This motion introduces submillimeter offsets in source positions in the PA direction. Theoretical modeling demonstrated that SR was achieved in M-DBT, but not in S-DBT, in the PA direction. This work shows that, with the use of magnification, anisotropies in SR are more sensitive to small offsets in the source motion, leading to insights into how to design M-DBT systems.

Conference Presentation

Citation Download Citation

Raymond J. Acciavatti, Trevor L. Vent, Chloe J. Choi, E. Paul Wileyto, Peter B. Noël, and Andrew D. A. Maidment "Development of magnification tomosynthesis for superior resolution in diagnostic mammography", Proc. SPIE 11595, Medical Imaging 2021: Physics of Medical Imaging, 115951J (15 February 2021); https://doi.org/10.1117/12.2580280

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available