Creation of new artificial calcification shadows for breast cancer and verification of effectiveness of CAD development technique that uses no actual cases

K. Abe; H. Takeo; Y. Nagai; Y. Kuroki; S. Nawano

doi:10.1117/12.2315790

6 July 2018 Creation of new artificial calcification shadows for breast cancer and verification of effectiveness of CAD development technique that uses no actual cases

K. Abe, H. Takeo, Y. Nagai, Y. Kuroki, S. Nawano

Author Affiliations +

Proceedings Volume 10718, 14th International Workshop on Breast Imaging (IWBI 2018); 1071817 (2018) https://doi.org/10.1117/12.2315790
Event: The Fourteenth International Workshop on Breast Imaging, 2018, Atlanta, Georgia, United States

Abstract

To compensate for an insufficiency of the case images needed in the development of CAD (Computer-Aided Diagnosis), work is underway to create artificial case images by embedding tumors and other such lesions into lesion-free images. Previously, the authors have demonstrated the effectiveness of creating artificial case images for hepatic and breast tumors and utilizing them in CAD development. Thus far, however, when training data comprising 50% or more artificial cases is used in CAD development, the resulting discrimination performance on test data has tended to be somewhat inferior compared to when training data comprises only actual cases.

With the objectives of applying artificial case images to a greater range of sites and of using exclusively artificial cases to develop a high-performance discriminator, in this study, effectiveness verification was conducted that focused on breast cancer calcifications as a new target. Because the characteristics of calcification shadows differ substantially from those of the hepatic and breast cancer tumor shadows studied thus far, a new artificial image creation technique was developed. Artificial cases created using this technique were applied to CAD development. As a result, a discriminator trained with 100% artificial cases obtained detection performance equal to that of a discriminator trained with entirely actual cases.

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K. Abe, H. Takeo, Y. Nagai, Y. Kuroki, and S. Nawano "Creation of new artificial calcification shadows for breast cancer and verification of effectiveness of CAD development technique that uses no actual cases", Proc. SPIE 10718, 14th International Workshop on Breast Imaging (IWBI 2018), 1071817 (6 July 2018); https://doi.org/10.1117/12.2315790

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KEYWORDS

Computer aided design

Computer aided diagnosis and therapy

Breast cancer

Tumors

Image processing

Machine learning

CAD systems

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