3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography

Yifeng Zeng; Bin Rao; Sreyankar Nandy; Ian Hagemann; Cary Siegel; Matthew Powell; Quing Zhu

doi:10.1117/12.2291718

1 March 2018 3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography

Yifeng Zeng, Bin Rao, Sreyankar Nandy, Ian Hagemann, Cary Siegel, Matthew Powell, Quing Zhu

Author Affiliations +

Proceedings Volume 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII; 1048338 (2018) https://doi.org/10.1117/12.2291718
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

It is important to provide timely information to surgeons on diagnosis of a suspicious ovarian tissue before excision to avoid unnecessary surgery, especially for young women. In this report, we introduce a new 3-D surface mapping technique to map ovarian tissue scattering properties by fitting the swept-source optical coherence tomography (SS-OCT) signals to a scattering model. We observed that lower scattering coefficients and heterogeneous spatial distribution were associated with malignant ovarian tissues, and higher scattering coefficients and homogeneous spatial distribution indicated benign ovarian tissues. The initial results suggest that the 3-D scattering map has potential to be an effective tool to characterize normal and malignant ovarian tissues.

Citation Download Citation

Yifeng Zeng, Bin Rao, Sreyankar Nandy, Ian Hagemann, Cary Siegel, Matthew Powell, and Quing Zhu "3D visualization of the ovarian tissue scattering coefficient with swept-source optical coherence tomography", Proc. SPIE 10483, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXII, 1048338 (1 March 2018); https://doi.org/10.1117/12.2291718

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