Geometric calibration and correction for a lens-coupled detector in x-ray phase-contrast imaging

Alex George; Peter Y. Chen; Alejandro Morales-Martinez; Alireza Panna; Andrew A. Gomella; Eric E. Bennett; Han Wen

doi:10.1117/1.JMI.4.1.013507

24 March 2017 Geometric calibration and correction for a lens-coupled detector in x-ray phase-contrast imaging

Alex George, Peter Y. Chen, Alejandro Morales-Martinez, Alireza Panna, Andrew A. Gomella, Eric E. Bennett, Han Wen

Author Affiliations +

Journal of Medical Imaging, Vol. 4, Issue 1, 013507 (March 2017). https://doi.org/10.1117/1.JMI.4.1.013507

Abstract

A lens-coupled x-ray camera with a tilted phosphor collects light emission from the x-ray illuminated (front) side of phosphor. Experimentally, it has been shown to double x-ray photon capture efficiency and triple the spatial resolution along the phosphor tilt direction relative to the same detector at normal phosphor incidence. These characteristics benefit grating-based phase-contrast methods, where linear interference fringes need to be clearly resolved. However, both the shallow incident angle on the phosphor and lens aberrations of the camera cause geometric distortions. When tiling multiple images of limited vertical view into a full-field image, geometric distortion causes blurring due to image misregistration. Here, we report a procedure of geometric correction based on global polynomial transformation of image coordinates. The corrected image is equivalent to one obtained with a single full-field flat panel detector placed at the sample plane. In a separate evaluation scan, the position deviations in the horizontal and vertical directions were reduced from 0.76 and 0.028 mm, respectively, to 0.006 and 0.009 mm, respectively, by the correction procedure, which were below the 0.028-mm pixel size of the imaging system. In a demonstration of a phase-contrast imaging experiment, the correction reduced blurring of small structures.

Citation Download Citation

Alex George, Peter Y. Chen, Alejandro Morales-Martinez, Alireza Panna, Andrew A. Gomella, Eric E. Bennett, and Han Wen "Geometric calibration and correction for a lens-coupled detector in x-ray phase-contrast imaging," Journal of Medical Imaging 4(1), 013507 (24 March 2017). https://doi.org/10.1117/1.JMI.4.1.013507

Received: 23 August 2016; Accepted: 2 March 2017; Published: 24 March 2017

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