The CUQI metric was tested on cardiac ultrasound sequences. In our tests, we used three cardiac ultrasound sequences consisting of 100 frames with a frame resolution of and frame rate of 25 frames per second. The video sequences were compressed at eight different quality levels using the latest video compression standard, HEVC.38 The quality levels were determined by the value of the QP used. Therefore, eight different QP values were used to impair the video at eight different quality levels. The QP values chosen were 27, 29, 31, 33, 35, 37, 39, and 41. The compression ratios achieved were in the range of 100∶1 to 550∶1 depending on the QP value used. For instance, the original video sequence, SeqA (refer to Fig. 3), was of file size 84,000 KB. At a QP level of , the file size was reduced to 834 KB. In total in the tests, we used 27 video sequences, i.e., three video sequences compressed at eight different quality levels. Figure 3 shows an example frame of the cardiac sequences considered in our tests.