Computer-Aided Diagnosis

Assessment of cervical demineralization induced by Streptococcus mutans using swept-source optical coherence tomography

[+] Author Affiliations
Hiroki Tezuka, Yasushi Shimada, Junji Tagami

Graduate School of Tokyo Medical and Dental University, Department of Cariology and Operative Dentistry, Tokyo, Japan

Khairul Matin

Graduate School of Tokyo Medical and Dental University, Department of Cariology and Operative Dentistry, Tokyo, Japan

Tsurumi University, School of Dental Medicine, Endowed Department of International Oral Health Science, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama-shi 230-8501, Japan

Masaomi Ikeda

Tokyo Medical and Dental University, Clinical Oral Science, Department of Oral Health Care Sciences, Faculty of Dentistry, Tokyo, Japan

Alireza Sadr

University of Washington School of Dentistry, Department of Restorative Dentistry, Seattle, Washington 98195, United States

Yasunori Sumi

National Center for Geriatrics and Gerontology, Department of Advanced Dental Research, Center of Advanced Medicine for Dental and Oral Diseases, Obu, Aichi, Japan

J. Med. Imag. 3(1), 014504 (Mar 08, 2016). doi:10.1117/1.JMI.3.1.014504
History: Received November 10, 2015; Accepted February 11, 2016
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Abstract.  Exposed root surfaces due to gingival recession are subject to biofilm stagnation that can result in caries formation. Cervical enamel and dentin demineralization induced by a cariogenic biofilm was evaluated using swept-source optical coherence tomography (SS-OCT). The cementoenamel junction (CEJ) sections of extracted human teeth were subjected to demineralization for 1, 2, or 3 weeks. A suspension of Streptococcus mutans was applied to form a cariogenic biofilm using an oral biofilm reactor. After incubation, demineralization was observed by SS-OCT. For the analysis of SS-OCT signal, the value of the area under the curve (AUC) of the signal profile was measured. Statistical analyses were performed with 95% level of confidence. Cervical demineralization was displayed as a bright zone in SS-OCT. The demineralization depth of dentin was significantly deeper than that of enamel (p<0.05). Enamel near the CEJ demonstrated a significant increase of AUC over the other enamel region after the demineralization. The gaps along the dentinoenamel junction were additionally observed in SS-OCT. SS-OCT was capable of monitoring the cervical demineralization induced by a cariogenic biofilm and is considered to be a promising modality for the diagnosis of cervical demineralization.

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© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Hiroki Tezuka ; Yasushi Shimada ; Khairul Matin ; Masaomi Ikeda ; Alireza Sadr, et al.
"Assessment of cervical demineralization induced by Streptococcus mutans using swept-source optical coherence tomography", J. Med. Imag. 3(1), 014504 (Mar 08, 2016). ; http://dx.doi.org/10.1117/1.JMI.3.1.014504


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