Physics of Medical Imaging

Quantitative simultaneous positron emission tomography and magnetic resonance imaging

[+] Author Affiliations
Jinsong Ouyang, Chuan Huang, Georges El Fakhri

Massachusetts General Hospital, Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston, Massachusetts 02114, United States

Harvard Medical School, Department of Radiology, Boston, Massachusetts 02114, United States

Yoann Petibon

Massachusetts General Hospital, Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston, Massachusetts 02114, United States

Sorbonne Universités, UPMC Univ Paris 06, Paris 75634, France

Timothy G. Reese

Harvard Medical School, Department of Radiology, Boston, Massachusetts 02114, United States

Massachusetts General Hospital, Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, Massachusetts 02129, United States

Aleksandra L. Kolnick

Massachusetts General Hospital, Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston, Massachusetts 02114, United States

J. Med. Imag. 1(3), 033502 (Nov 03, 2014). doi:10.1117/1.JMI.1.3.033502
History: Received April 22, 2014; Revised August 19, 2014; Accepted October 2, 2014
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Abstract.  Simultaneous positron emission tomography and magnetic resonance imaging (PET-MR) is an innovative and promising imaging modality that is generating substantial interest in the medical imaging community, while offering many challenges and opportunities. In this study, we investigated whether MR surface coils need to be accounted for in PET attenuation correction. Furthermore, we integrated motion correction, attenuation correction, and point spread function modeling into a single PET reconstruction framework. We applied our reconstruction framework to in vivo animal and patient PET-MR studies. We have demonstrated that our approach greatly improved PET image quality.

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© 2014 Society of Photo-Optical Instrumentation Engineers

Citation

Jinsong Ouyang ; Yoann Petibon ; Chuan Huang ; Timothy G. Reese ; Aleksandra L. Kolnick, et al.
"Quantitative simultaneous positron emission tomography and magnetic resonance imaging", J. Med. Imag. 1(3), 033502 (Nov 03, 2014). ; http://dx.doi.org/10.1117/1.JMI.1.3.033502


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